How to cure Hemophilia

Hemophilia is an uncommon bleeding disorder, which stops the blood from clotting. It is a group of traditional genetic disorders that damage the body’s capability to control blood clotting or coagulation, which is used to discontinue bleeding when a blood vessel is busted. Internal bleeding can start without any apparent cause spreading to the joint and tissues.Hemophilia A is the most common form of hemophilia, which is caused by the deficiency of factor VIII which is a blood plasma protein. The next common form of hemophilia is – Hemophilia B that is the result of the deficiency of factor IX blood plasma protein.

Transplanted cells: Recent research by scientists has proved for the first time that transplanted cells can cure hemophilia. This transplantation has been conducted over the mice and has shown successful results.

Hemophilia A has been cured by transplanting healthy liver endothial cells from the donor to the recipient mouse. After the three months of transplantation, by examining the liver of the recipient mouse, it was found that the transplanted cells have engrafted and increased in the number. However, the scientists are of the opinion that more work needs are required before the liver-cell transplants can be attempted on the people.

Gene Therapy cure: Most of the research that had been carried out for the curing of hemophilia has been centering around gene therapy. This therapy is simply wonderful.

People who are suffering from hemophilia have low levels of some clotting proteins usually factor VIII and factor IX which are responsible for the clotting of the blood. A person not suffering from this disease continuously produces these proteins in the body. Livers in particular and other cells of our body contribute to the production of this protein.

In gene therapy, a single cell (usually liver, and also other cells of muscle, fat can also be considered) is removed from a person suffering from hemophilia.

The cells are then genetically changed by inserting a new genetic matter into them to reprogram the cells. This new genetic material initiates the cells to produce factor VIII or factor IX. After that, these cells are inserted into the person having hemophilia and there is no hemophilia in that person.

The gene therapy has been successfully proved on animals as well as humans. The genetically altered cells survive and reproduce. Some of the blood clotting factors have even thrived for three years and are still being experimented.

Presently there is no cure for this disease but gene therapy is still thought of as an exciting possibility and holds out the prospect of a partial or complete cure for hemophilia disease. In fact, one assumes that a time will come when a person suffering from hemophilia will go to the treatment center and come out without the genetic disorder.