Rhabdomyolysis Symptoms, Causes And Treatments

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Rhabdomyolysis is a medical condition in which the muscle tissue breaks down rapidly. Three kinds of muscles exist in our body – Smooth muscle, skeletal muscle and heart muscle. Rhabdomyolysis degenerates the skeletal muscles. Of the three kinds of muscles that exist in our body, the skeletal muscles help in movement of the body.



Rhabdomyolysis The tissue break down leads to release of a protein called Myoglobin into the blood stream. It usually occurs when there is an injury caused to the skeletal muscular structure of the body.

Symptoms

Kidney Failure

The protein that is released in the blood stream due to muscle loss gets carried away into the kidney along with the blood. As you know, kidney filters the blood and so myoglobin also gets washed out. The colour of urine tends to be very dark due to protein content in it. However, the excessive protein in the blood damages kidney over a period of time ultimately leading to its failure. If you have been diagnosed with a kidney related disease, there is a heightened chance of you having Rhabdomyolysis.



Kidney Failure

Muscle Pain

Muscle breakdown in Rhabdomyolysis leads to persistent pain in the skeletal muscles. Stiffness becomes quite common even if you have been stagnant in one posture for a very short time. No amount of rest and general pain treatment help in the muscle pain. The pain returns right after the affect of pain killers wear off. In initial stages of this disease, muscle ache is not experienced. Swelling of joints is also common in this condition. Muscle Pain

Erratic Blood Supply

The release of myoglobin coupled with swelling in muscles can obstruct the blood supply in certain parts of the body. The swollen muscles exert pressure on the nerves and blood vessels whereas the myoglobin increases the impurity of the blood leading to erratic flow of blood and causes numbness and tingling sensation in those parts. This is also referred to as compartment syndrome.

Erratic Blood Supply

Other Symptoms

Fatigue, low urine production, confusion, arrhythmia, confusion, nausea, vomiting and low blood pressure are some of the other commonly reported symptoms of people suffering from Rhabdomyolysis.

Other Symptoms

Causes

Crush Injury

This is the most common cause of Rhabdomyolysis. Crush injury is said to have happened when a person had an injury that led to compression of certain part of the body for a long time. For e.g. getting trapped under fallen debris, building construction material or getting ran over by a vehicle. This type of an injury greatly damages the muscle tissue of the body.

Crush Injury

Genetic Factors

This disease is also known to occur in the family trees from one generation to another. When this condition is contracted genetically, it is called familial paroxysmal Rhabdomyolysis. Though it is rare, but mostly inflicts small children and is life threatening to them.


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Genetic Factors

Other Causes

Physical Exertion

Where a particular part of body bears the pressure persistently over a long duration.

Hypothyroidism

Hypothyroidism It is a condition where thyroid does not produce sufficient thyroxin which in turns leads to muscle breakdown.

Drugs And Medication

Consumption of drugs for controlling cholesterol, diuretics, neuromuscular blocking agents and anti-psychotic drugs can accelerate and cause Rhabdomyolysis.

Drugs And Medication

Treatment

Mostly a urine test can reveal the presence of high protein level and thus confirm existence of Rhabdomyolysis. Under this section lets discuss various treatment options available. The treatments will depend on the causes of Rhabdomyolysis.

Treatment

Intravenous Fluids

Introduction of additional fluids into the blood stream is done to increase the rate of filtration process. This filters and dilutes the myoglobin and other renal tubular toxins. The dilution slows down the breakage of muscular tissue thereby improving the symptoms associated with Rhabdomyolysis. This approach is especially helpful in cases of crush injury.

Intravenous Fluids

Dialysis

Where there has been an extensive damage to kidney interrupting the filtering process of blood or a complete kidney failure due to Rhabdomyolysis, the patient is put on dialysis. This process cleans the blood artificially replacing the function of kidney.

Dialysis

Treating Hypothyroidism

If Rhabdomyolysis is caused by hypothyroidism, then the treatment of this condition is done to alleviate the symptoms. Since there is insufficient thyroxin in the body, a dose of this hormone called T3 and T4 is injected in order to bring this hormone up to an acceptable level. Treating Hypothyroidism

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Caution: Please use Home Remedies after Proper Research and Guidance. You accept that you are following any advice at your own risk and will properly research or consult healthcare professional.

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